Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001942 | 0.86 | CYP3A4 (0.45) | PPARGSMN1; SMN2KMT2AHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9001969 | 0.85 | SCN1A (0.46) | PPARGSMN1; SMN2KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9001901 | 0.80 | CYP3A4 (0.48) | PPARGSMN1; SMN2QPCTKMT2AHSD17B10 | |
| SCHEMBL9001975 | 0.80 | KMT2A (0.47) | POLBSMN1; SMN2TSHRKMT2AHSD17B10 | |
| SCHEMBL9002062 | 0.80 | PPARG (0.37) | PPARGPOLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9002027 | 0.80 | CNR2 (0.36) | PPARGSMN1; SMN2TSHRKMT2AHSD17B10 | |
| SCHEMBL9002030 | 0.80 | CYP3A4 (0.50) | PPARGSMN1; SMN2QPCTKMT2AHSD17B10 | |
| SCHEMBL9002286 | 0.79 | ALDH1A1 (0.50) | POLBSMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL9002172 | 0.79 | MAPT (0.43) | PPARGPOLBTSHRKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9002295 | 0.78 | ALDH1A1 (0.49) | POLBSMN1; SMN2KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |