Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9001908 | 0.99 | MAPT (0.42) | MAPTALDH1A1HSD17B10RECQLPOLB | |
| SCHEMBL9002013 | 0.93 | POLB (0.37) | MAPTALDH1A1HSD17B10RECQLPOLB | |
| SCHEMBL9002010 | 0.91 | POLB (0.36) | MAPTALDH1A1HSD17B10RECQLPOLB | |
| SCHEMBL9002027 | 0.89 | CNR2 (0.36) | MAPTALDH1A1HSD17B10LMNACDK8 | |
| SCHEMBL9002019 | 0.88 | ALDH1A1 (0.35) | MAPTALDH1A1HSD17B10RECQLCDK8 | |
| SCHEMBL9002262 | 0.86 | NPY5R (0.33) | MAPTALDH1A1HSD17B10CDK8ROCK1 | |
| SCHEMBL9002373 | 0.85 | KDM4E (0.36) | MAPTALDH1A1HSD17B10CDK8ROCK1 | |
| SCHEMBL9002538 | 0.84 | CDK8 (0.33) | MAPTALDH1A1CDK8ROCK1CHEK1 | |
| SCHEMBL9001975 | 0.84 | KMT2A (0.47) | MAPTALDH1A1HSD17B10POLBTDP1 | |
| SCHEMBL9002239 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | claimed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | claimed |
| JP-5051383-A | — | — | None | — | — | JP | disclosed |
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5191018-A | IMPACT-RESISTANT GRAFT COPOLYMER AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-02 | — | — | US | disclosed |
| JP-H0551383-A | IMIDAZO (1,2-A) PYRIDINE DERIVATIVE AND CALMODULIN-INHIBITING AGENT CONTAINING THE SAME | TAKEDA CHEM IND LTD | 1993-03-02 | — | — | JP | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |