Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001975 | 0.90 | KMT2A (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL9002239 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL9002007 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL9002286 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PKML3MBTL1 | |
| SCHEMBL9002174 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL9002295 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1PKML3MBTL1 | |
| Hydrochloric Acid SCHEMBL9179842 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL9002062 | 0.83 | PPARG (0.37) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL9002172 | 0.81 | MAPT (0.43) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL9002027 | 0.80 | CNR2 (0.36) | ALDH1A1KMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |