Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PER2 | O15055 | 1/20 | 0.48 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.48 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312253 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBCA2GAA | |
| SCHEMBL12136891 | 0.84 | GAA (0.51) | ALDH1A1SMN1; SMN2POLBGAAAPLNR | |
| SCHEMBL13236420 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBCA2CNR2 | |
| SCHEMBL10312252 | 0.84 | CNR2 (0.62) | ALDH1A1SMN1; SMN2POLBCA2GAA | |
| SCHEMBL18221854 | 0.82 | CA2 (0.56) | ALDH1A1SMN1; SMN2POLBCA2GAA | |
| SCHEMBL2103432 | 0.79 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2POLBCA2GAA | |
| SCHEMBL5628412 | 0.79 | CA2 (0.49) | ALDH1A1SMN1; SMN2POLBCA2CNR2 | |
| SCHEMBL4499222 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2POLBCA2GAA | |
| SCHEMBL5672853 | 0.79 | HTT (0.55) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12406937 | 0.79 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2POLBCA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |