Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001911 | 0.85 | RECQL (0.43) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9002171 | 0.85 | MAPT (0.41) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9001904 | 0.82 | MAPT (0.39) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL9001897 | 0.81 | HSD17B10 (0.37) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9002068 | 0.77 | HSD17B10 (0.34) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9002172 | 0.75 | MAPT (0.43) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL9001908 | 0.74 | MAPT (0.42) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9001984 | 0.69 | MAPK1 (0.46) | ALDH1A1MAPTHSD17B10RECQLKMT2A | |
| SCHEMBL9002478 | 0.69 | CYP3A4 (0.46) | ALDH1A1HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL9002285 | 0.69 | RECQL (0.37) | ALDH1A1MAPTHSD17B10RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |