Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001887 | 0.80 | NPC1 (0.38) | HSD17B10ALDH1A1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9001897 | 0.79 | HSD17B10 (0.37) | HSD17B10ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL9002528 | 0.77 | ALDH1A1 (0.41) | HSD17B10ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL9002171 | 0.77 | MAPT (0.41) | HSD17B10ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL9001911 | 0.77 | RECQL (0.43) | HSD17B10ALDH1A1MAPTPDCD1CD274 | |
| SCHEMBL9001904 | 0.74 | MAPT (0.39) | HSD17B10ALDH1A1MAPTLMNACYP1A2 | |
| SCHEMBL9002172 | 0.67 | MAPT (0.43) | HSD17B10ALDH1A1MAPTLMNAUSP2 | |
| Hydrochloric Acid SCHEMBL9001908 | 0.66 | MAPT (0.42) | HSD17B10ALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL9002285 | 0.64 | RECQL (0.37) | HSD17B10ALDH1A1MAPTLMNARECQL | |
| SCHEMBL9001984 | 0.62 | MAPK1 (0.46) | HSD17B10ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |