SCHEMBL9002597

SCHEMBL9002597

CC1(C)CC(NC(=O)c2ccc(C(=O)NN)cc2)CC(C)(C)N1

nearest known ligand 0.76

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 9/20 0.70
GLA P06280 1/20 0.64
POLB P06746 1/20 0.62
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
CYP2C9 P11712 1/20 0.60
L3MBTL1 Q9Y468 3/20 0.59
ATM Q13315 1/20 0.57
PKM P14618 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169747 0.92 EZH2 (0.80) EZH2GLAPOLBMEN1KMT2A
SCHEMBL27636094 0.88 EZH2 (0.70) EZH2GLAPOLBMEN1KMT2A
SCHEMBL6121185 0.86 EZH2 (0.72) EZH2GLAPOLBMEN1KMT2A
SCHEMBL14679120 0.86 POLB (0.73) EZH2GLAPOLBMEN1KMT2A
SCHEMBL17067286 0.85 MEN1 (0.71) EZH2GLAPOLBMEN1KMT2A
SCHEMBL13683724 0.85 EZH2 (0.70) EZH2GLAPOLBMEN1KMT2A
SCHEMBL6120701 0.85 EZH2 (0.70) EZH2GLAPOLBMEN1KMT2A
SCHEMBL6119923 0.85 EZH2 (0.62) EZH2GLAPOLBMEN1KMT2A
SCHEMBL2908330 0.84 EZH2 (0.89) EZH2GLAPOLBMEN1KMT2A
SCHEMBL8738669 0.84 EZH2 (0.68) EZH2GLAPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
US-5318851-A Curable composition with auxiliary curing agent; coatings ELF ATOCHEM N.A., INC. (US) 1994-06-07 US disclosed
US-5300545-A Mixing with a N-(2,2,6,6-tetraalkyl-4-piperidinyl)amide-hydrazides stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-05 US disclosed
US-5214147-A Reacting piperdinyl half-ester half-amide with hydrazine; heat and light stabilizers for anhydride copolymers by chemical attachment of hydrazide functional group ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-05-25 US disclosed
US-5213897-A Curable coating compositions containing an N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazide ELF ATOCHEM NORTH AMERICA, INC. 1993-05-25 US disclosed
EP-0516192-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-12-02 EP disclosed
EP-0507333-A2 Epoxy resins containing bound light stabilizing groups ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-10-07 EP disclosed
US-5132387-A Polyme bound ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-21 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
US-5101033-A Piperidinyl-N-aminooxamides ATOCHEM NORTH AMERICA, INC. (US) 1992-03-31 US disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
WO-1990009408-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed