Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.42 |
| ▸ | ITGAV | P06756 | 5/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002785 | 1.00 | ITGB3 (0.42) | ITGB3ITGA2BITGAVITGB5ITGA5 | |
| SCHEMBL8002679 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BITGAVITGB5ITGA5 | |
| SCHEMBL4281521 | 0.70 | HDAC6 (0.62) | ITGB3ITGAVGAAHDAC1HDAC8 | |
| SCHEMBL18894019 | 0.70 | HDAC6 (0.62) | ITGB3ITGAVGAAHDAC1HDAC8 | |
| SCHEMBL26915184 | 0.70 | HDAC6 (0.62) | ITGB3ITGAVGAAHDAC1HDAC8 | |
| SCHEMBL30839645 | 0.70 | SMN1; SMN2 (0.52) | HDAC1HDAC8HDAC6 | |
| SCHEMBL2687510 | 0.68 | GAA (0.36) | ITGB3ITGA2BITGAVITGB5ITGA5 | |
| SCHEMBL6140289 | 0.67 | HDAC6 (0.53) | ITGB3ITGA2BITGAVITGB1GAA | |
| SCHEMBL6140790 | 0.67 | HDAC6 (0.53) | ITGB3ITGA2BITGAVITGB1GAA | |
| SCHEMBL15346086 | 0.67 | ITGB3 (0.50) | ITGB3ITGA2BITGAVITGB5ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |