Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.42 |
| ▸ | PIM1 | P11309 | 5/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161321 | 0.82 | SIRT3 (0.46) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| SCHEMBL353138 | 0.82 | SIRT3 (0.46) | SIRT3TDP1KDM4EL3MBTL1MKNK1 | |
| SCHEMBL31606794 | 0.82 | SIRT3 (0.46) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| SCHEMBL5169958 | 0.80 | SIRT3 (0.44) | SIRT3TDP1KDM4EL3MBTL1MKNK1 | |
| SCHEMBL14917426 | 0.80 | MKNK1 (0.41) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| Hydrochloric Acid SCHEMBL5012214 | 0.80 | NTRK1 (0.44) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| Hydrochloric Acid SCHEMBL5796678 | 0.80 | SIRT3 (0.44) | SIRT3TDP1KDM4EL3MBTL1MKNK1 | |
| Hydrochloric Acid SCHEMBL5012204 | 0.80 | NTRK1 (0.44) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| SCHEMBL29089331 | 0.80 | NTRK1 (0.44) | SIRT3TDP1NTRK1PIM1ACVR1 | |
| Ammonia Solution, Strong SCHEMBL27581013 | 0.80 | NTRK1 (0.44) | SIRT3TDP1NTRK1PIM1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516901-A | Preparation of reactive phthalocyanine dyes | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| CN-1088235-A | The preparation of reactive phthalocyanine dyes | BASF AG (DE) | 1994-06-22 | — | — | CN | disclosed |
| US-5302708-A | Colorfastness | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | disclosed |
| US-4745187-A | Process for the preparation of water-soluble phthalocyanine dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |