Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474346 | 0.85 | IDO1 (0.35) | HTR2AHTR2CHTR2BIDO1SLC6A2 | |
| SCHEMBL900287 | 0.83 | HTR2A (0.34) | HTR2AHTR2CHTR2BDDR1 | |
| SCHEMBL900763 | 0.77 | HTR2A (0.35) | HTR2AHTR2CHTR2BPDE2ADDR1 | |
| SCHEMBL900737 | 0.75 | PDE2A (0.34) | PDE2A | |
| SCHEMBL5415297 | 0.75 | FFAR4 (0.45) | FFAR4SLC6A2SLC6A4 | |
| SCHEMBL10525468 | 0.74 | PDE2A (0.46) | PDE2AIDO1 | |
| SCHEMBL900575 | 0.73 | IDO1 (0.32) | HTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL900206 | 0.71 | KCNK2 (0.31) | PDE2A | |
| SCHEMBL900738 | 0.71 | PDE2A (0.37) | HTR2AHTR2CHTR2BPDE2AFFAR4 | |
| SCHEMBL17887543 | 0.71 | RIPK1 (0.43) | HTR2AHTR2CHTR2BDDR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |