SCHEMBL900297

SCHEMBL900297

O=C(O)[C@H]1C[C@H](F)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305909 1.00
SCHEMBL6196827 1.00
SCHEMBL901476 1.00
SCHEMBL187962 1.00
SCHEMBL661917 1.00
SCHEMBL16635328 1.00
SCHEMBL187963 1.00
SCHEMBL901466 1.00
Hydrochloric Acid SCHEMBL6201099 0.98 CYP2D6 (0.56)
Hydrochloric Acid SCHEMBL21598085 0.98 CYP2D6 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149881-B Chiral derivatization reagent and preparation method and application thereof 宁波大学 2022-07-19 CN claimed
CN-113149881-A Chiral derivatization reagent and preparation method and application thereof 宁波大学 2021-07-23 CN claimed
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN disclosed
US-20250152658-A1 CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-15 US disclosed
EP-3647319-B1 PEPTIDE COMPOUND, APPLICATION THEREOF AND COMPOSITION CONTAINING SAME XDCEXPLORER SHANGHAI CO LTD (CN) 2025-04-09 EP disclosed
WO-2025046244-A1 TLR3 BINDING BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2025-03-06 WO disclosed
US-12129312-B2 Peptide compound, application thereof and composition containing same XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2024-10-29 US disclosed
US-20240287138-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY MERCK SHARP & DOHME LLC 2024-08-29 US disclosed
US-20240209023-A1 PEPTIDE COMPOUND, APPLICATION THEREOF AND COMPOSITION CONTAINING SAME XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2024-06-27 US disclosed
US-20230391828-A1 REGULATORS OF CELL DIVISION TECHNISCHE UNIVERSITAT DRESDEN (DE) 2023-12-07 US disclosed
CN-116390742-A Cyclic chemokine-9 derivatives 拜耳公司 2023-07-04 CN disclosed
WO-2013020062-A1 QUINAZOLINE COMPOUNDS AS SERINE/THREONINE KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2013-02-07 WO disclosed
WO-2012041789-A1 HERBICIDAL BENZOXAZINONES BASF SE (DE) 2012-04-05 WO disclosed
EP-0973739-B1 N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES DEGUSSA (DE) 2005-11-02 EP disclosed
US-6664400-B2 1-((4-halo-3-sulfonamidophenyl)aminocarbonyl),2-carboxy -pyrrolidine intermediate of given formula DEGUSSA AG (DE) 2003-12-16 US disclosed
US-20020137946-A1 N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives DEGUSSA AG (DE) 2002-09-26 US disclosed
US-6384234-B1 HALOGENATION DEGUSSA AG (DE) 2002-05-07 US disclosed
CN-1248244-A N-arylsulfonamide- and pyrrolidinecarboxylic acid intermediates, and their use for preparation of herbicidal 1,3-dioxo-1H-pyrrolo [1,2-c] imidazole derivatives DU PONT (US) 2000-03-22 CN disclosed
EP-0973739-A1 N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-01-26 EP disclosed
WO-1998037065-A1 N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-08-27 WO disclosed