Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953956 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8953911 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8954050 | 0.89 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8954509 | 0.89 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL9003118 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL9002995 | 0.88 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8635509 | 0.88 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8924564 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL3243184 | 0.88 | PTGS2 (0.82) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8954915 | 0.88 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731793-A1 | 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | claimed |
| WO-1995015315-A1 | 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | claimed |
| US-5475018-A | Antiinflammatory agent, antiarthritic agent; analgesics and antipyretics | G. D. SEARLE & CO. (US) | 1995-12-12 | — | — | US | disclosed |