SCHEMBL9003029

SCHEMBL9003029

CC(C)(C)OC(=O)N1CC2[C@H](C1)[C@H](F)CCC2(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.45
RORC P51449 11/20 0.43
GPR119 Q8TDV5 1/20 0.42
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX15 P16050 1/20 0.40
ATM Q13315 1/20 0.40
TACR1 P25103 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9262375 1.00 USP30 (0.45) USP30RORCGPR119FNTAFNTB
SCHEMBL9003033 1.00 USP30 (0.45) USP30RORCGPR119FNTAFNTB
SCHEMBL9003205 1.00 USP30 (0.45) USP30RORCGPR119FNTAFNTB
SCHEMBL9270074 1.00 USP30 (0.45) USP30RORCGPR119FNTAFNTB
SCHEMBL9002998 0.88 RORC (0.43) USP30RORCGPR119FNTAFNTB
SCHEMBL9267451 0.88 RORC (0.43) USP30RORCGPR119FNTAFNTB
SCHEMBL9003003 0.88 RORC (0.43) USP30RORCGPR119FNTAFNTB
SCHEMBL9268937 0.88 RORC (0.43) USP30RORCGPR119FNTAFNTB
SCHEMBL9003159 0.88 RORC (0.43) USP30RORCGPR119FNTAFNTB
SCHEMBL9003390 0.87 RORC (0.45) USP30RORCGPR119FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508433-A Derivatives of perhydroisoindole and preparation thereof RHONE-POULENC RORER S.A. (FR) 1996-04-16 US disclosed