Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271264 | 1.00 | RORC (0.45) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9003003 | 0.88 | RORC (0.43) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9003159 | 0.88 | RORC (0.43) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9267451 | 0.88 | RORC (0.43) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9002998 | 0.88 | RORC (0.43) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9268937 | 0.88 | RORC (0.43) | RORCGPR119NAMPTFNTAFNTB | |
| SCHEMBL9003033 | 0.87 | USP30 (0.45) | RORCGPR119FNTAFNTBTSHR | |
| SCHEMBL9262375 | 0.87 | USP30 (0.45) | RORCGPR119FNTAFNTBTSHR | |
| SCHEMBL9003029 | 0.87 | USP30 (0.45) | RORCGPR119FNTAFNTBTSHR | |
| SCHEMBL9270074 | 0.87 | USP30 (0.45) | RORCGPR119FNTAFNTBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | disclosed |