SCHEMBL9003099

SCHEMBL9003099

O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)N1CCCCCC1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 17/20 0.58
DPP4 P27487 1/20 0.53
KCNH2 Q12809 1/20 0.53
DPP7 Q9UHL4 1/20 0.53
CTSK P43235 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7145146 1.00 CASP1 (0.58) CASP1DPP4KCNH2DPP7CTSK
SCHEMBL9003092 1.00 CASP1 (0.58) CASP1DPP4KCNH2DPP7CTSK
SCHEMBL7145151 1.00 CASP1 (0.58) CASP1DPP4KCNH2DPP7CTSK
SCHEMBL25185922 0.99 CASP1 (0.59) CASP1DPP4KCNH2DPP7CTSK
SCHEMBL7140119 0.90 ALDH1A1 (0.53) CASP1DPP4KCNH2DPP7
SCHEMBL7140126 0.90 ALDH1A1 (0.53) CASP1DPP4KCNH2DPP7
SCHEMBL25186498 0.88 MEN1 (0.56) CASP1
SCHEMBL6793150 0.88 DPP4 (0.58) DPP4KCNH2DPP7CTSK
SCHEMBL25186534 0.87 CASP1 (0.53) CASP1CTSK
SCHEMBL25185732 0.86 CASP1 (0.55) CASP1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559232-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-09-24 US disclosed