Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613454 | 1.00 | — | — | |
| SCHEMBL233934 | 1.00 | CES2 (0.33) | CES2CES1EPHX1HIF1AALDH1A1 | |
| SCHEMBL31069807 | 1.00 | CES2 (0.33) | CES2CES1EPHX1HIF1AALDH1A1 | |
| SCHEMBL187726 | 1.00 | — | — | |
| SCHEMBL5125 | 0.96 | — | — | |
| SCHEMBL3003606 | 0.93 | — | — | |
| SCHEMBL170348 | 0.89 | — | — | |
| SCHEMBL18019588 | 0.86 | THRB (0.32) | ALDH1A1 | |
| Bromide SCHEMBL6668400 | 0.83 | — | — | |
| Bromide SCHEMBL6668403 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497565-B1 | Foamable silicone rubber composition and silicone rubber sponge | SHINETSU CHEMICAL CO (JP) | 1996-09-25 | — | — | EP | disclosed |