SCHEMBL900338

SCHEMBL900338

Nc1ccc(CCc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.61
MAOB P27338 4/20 0.58
MAOA P21397 2/20 0.58
ALDH1A1 P00352 2/20 0.54
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
RARB P10826 6/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
PPARA Q07869 1/20 0.49
MEN1 O00255 1/20 0.49
RARA P10276 1/20 0.49
MAPT P10636 1/20 0.49
MTOR P42345 1/20 0.49
KMT2A Q03164 1/20 0.49
ANPEP P15144 1/20 0.47
ENPEP Q07075 1/20 0.47
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19143887 0.92 RARB (0.58) GFERMAOBMAOAALDH1A1TP53
Terephthalic Acid SCHEMBL4612225 0.89 TSHR (0.67) ALDH1A1TP53TSHRRARBPPARA
SCHEMBL70166 0.89 TSHR (0.67) ALDH1A1TP53TSHRRARBPPARA
SCHEMBL6864579 0.87 TSHR (0.61) ALDH1A1TP53TSHRMAPTKMT2A
Hydrochloric Acid SCHEMBL7132238 0.86 TSHR (0.63) ALDH1A1TP53TSHRRARBPPARA
Terephthalic Acid SCHEMBL9717815 0.86 TSHR (0.71) ALDH1A1TP53TSHRMEN1MAPT
Terephthalic Acid SCHEMBL7648718 0.86 TSHR (0.71) ALDH1A1TP53TSHRMEN1MAPT
Aminobenzoic Acid SCHEMBL1768920 0.86 TSHR (0.71) ALDH1A1TP53TSHRMEN1MAPT
Aminobenzoic Acid SCHEMBL8249 0.86 TSHR (0.71) ALDH1A1TP53TSHRMEN1MAPT
Tyramine SCHEMBL8001426 0.85 ALDH1A1 (0.62) GFERMAOBMAOAALDH1A1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500627-A1 ADDUCTS AND USES THEREOF Huntsman Advanced Materials Americas LLC (US) 2019-06-26 EP disclosed
WO-2018035397-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2018-02-22 WO disclosed
EP-2772490-B1 AMINOALKYL-SUBSTITUTED N-THIENYL BENZAMIDE DERIVATIVE ASTELLAS PHARMA INC (JP) 2016-04-06 EP disclosed
US-9062032-B2 Aminoalkyl-substituted N-thienylbenzamide derivative ASTELLAS PHARMA INC. (JP) 2015-06-23 US disclosed
US-9062032-B2 Aminoalkyl-substituted N-thienylbenzamide derivative ASTELLAS PHARMA INC. (JP) 2015-06-23 US disclosed
US-20150031727-A1 AMINOALKYL-SUBSTITUTED N-THIENYLBENZAMIDE DERIVATIVE ASTELLAS PHARMA INC. (JP) 2015-01-29 US disclosed
US-20150031727-A1 AMINOALKYL-SUBSTITUTED N-THIENYLBENZAMIDE DERIVATIVE ASTELLAS PHARMA INC. (JP) 2015-01-29 US disclosed
EP-2772490-A1 AMINOALKYL-SUBSTITUTED N-THIENYL BENZAMIDE DERIVATIVE Astellas Pharma Inc. (JP) 2014-09-03 EP disclosed
EP-2726529-A1 HYBRID EPOXY RESINS Dow Global Technologies LLC (US) 2014-05-07 EP disclosed
EP-2726530-A1 HYBRID EPOXY RESIN ADDUCTS Dow Global Technologies LLC (US) 2014-05-07 EP disclosed
WO-2012047420-A2 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-12 WO disclosed
WO-2012044443-A1 EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
WO-2011136843-A1 EPOXY POLYCYCLOPENTADIENE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
WO-2011068645-A1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
WO-2011068644-A1 EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
WO-2011068643-A2 COMPOSITE COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
EP-2291426-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME Dow Global Technologies Inc. (US) 2011-03-09 EP disclosed
EP-2283060-A1 ADDUCTS OF EPOXY RESINS AND PROCESS FOR PREPARING THE SAME Dow Global Technologies Inc. (US) 2011-02-16 EP disclosed
WO-2009143038-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-26 WO disclosed
WO-2009142898-A1 ADDUCTS OF EPOXY RESINS AND PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031727-A1 AMINOALKYL-SUBSTITUTED N-THIENYLBENZAMIDE DERIVATIVE SLC34A2, SLC10A2, ALPI GFER 2766/4885MAOB 2380/4885MAOA 3967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.