SCHEMBL9003477

SCHEMBL9003477

CC(C)(c1ccc(OCCOc2ccccc2)cc1)c1cc(C(=O)O)c(O)c(C2CCCCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.43
POLB P06746 2/20 0.43
ALDH1A1 P00352 8/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 7/20 0.42
KMT2A Q03164 7/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 6/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
MAPT P10636 1/20 0.40
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
EPHX2 P34913 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535569 0.87 ACMSD (0.46) KDM4EALDH1A1MEN1KMT2APTGDR2
SCHEMBL10811963 0.85 ACMSD (0.45) KDM4EALDH1A1MEN1KMT2APTGDR2
SCHEMBL9003455 0.82 KDM4E (0.50) KDM4EPOLBALDH1A1TDP1MEN1
SCHEMBL9003340 0.80 KDM4E (0.48) KDM4EPOLBALDH1A1TDP1MEN1
SCHEMBL9003376 0.80 KDM4E (0.48) KDM4EPOLBALDH1A1TDP1MEN1
SCHEMBL9003457 0.79 KDM4E (0.47) KDM4EPOLBALDH1A1TDP1MEN1
SCHEMBL9003553 0.79 KMT2A (0.47) KDM4EPOLBALDH1A1TDP1MEN1
SCHEMBL8973123 0.77 KDM4E (0.52) KDM4EPOLBALDH1A1TDP1MEN1
Zinc Ion SCHEMBL10353282 0.77 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2APTGDR2
SCHEMBL9003533 0.76 KDM4E (0.49) KDM4EPOLBALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424914-B1 Recording material NEW OJI PAPER CO LTD (JP) 1996-09-25 EP disclosed
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
US-5096872-A Colorless basic dye reacts with salicylic acid derivative to form colored image, paper KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-17 US disclosed
EP-0424914-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1991-05-02 EP disclosed