SCHEMBL9003533

SCHEMBL9003533

C=CCc1cc(C(C)(C)c2ccc(OCCOc3ccccc3)cc2)cc(C(=O)O)c1O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.49
ALDH1A1 P00352 9/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
GAA P10253 2/20 0.48
POLB P06746 3/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
HTT P42858 2/20 0.43
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PKM P14618 1/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
THRB P10828 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10463863 0.84 ALOX15 (0.39) KDM4EALDH1A1POLBMEN1KMT2A
SCHEMBL9003455 0.83 KDM4E (0.50) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003392 0.82 ALDH1A1 (0.43) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003376 0.81 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003340 0.81 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003457 0.80 KDM4E (0.47) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003553 0.80 KMT2A (0.47) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL8973123 0.78 KDM4E (0.52) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003579 0.77 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL9003477 0.76 KDM4E (0.43) KDM4EALDH1A1SMN1; SMN2GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424914-B1 Recording material NEW OJI PAPER CO LTD (JP) 1996-09-25 EP disclosed
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
US-5096872-A Colorless basic dye reacts with salicylic acid derivative to form colored image, paper KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-17 US disclosed
EP-0424914-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1991-05-02 EP disclosed