SCHEMBL9003592

SCHEMBL9003592

Nc1ccc(-c2cc(C(=O)O)ccc2C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
MAPT P10636 4/20 0.48
ALDH1A1 P00352 4/20 0.48
RECQL P46063 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
GAA P10253 2/20 0.48
GFER P55789 2/20 0.48
POLB P06746 2/20 0.48
HPGD P15428 2/20 0.48
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48
NPC1 O15118 1/20 0.48
MITF O75030 1/20 0.48
NFKB1 P19838 1/20 0.48
RAB9A P51151 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
PAX8 Q06710 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL28960885 0.94 KDM4E (0.43) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL6225855 0.91 KDM4E (0.50) KDM4EMAPTGAAPOLBPTPN1
SCHEMBL599317 0.89 FOLH1 (0.53) KDM4EFOLH1HSD17B10DDTRXRA
SCHEMBL6443680 0.87 ALDH1A1 (0.57) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL28284951 0.86 KDM4E (0.49) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL14972646 0.85 CSNK2A2 (0.54) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL1683894 0.85 KDM4E (0.59) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL29626098 0.85 KDM4E (0.59) KDM4EMAPTALDH1A1RECQLTDP1
SCHEMBL30777933 0.84 HNF4A (0.55) KDM4EMAPTALDH1A1PTPN1MCL1
SCHEMBL9389773 0.84 HSD17B10 (0.59) KDM4EMAPTALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026272-A Polyimide resin and Kapton 三菱瓦斯化学株式会社 2018-05-11 CN disclosed
CN-104837894-B Polyimide precursor, polyimide film, varnish, and substrate 宇部兴产株式会社 2018-02-23 CN disclosed
CN-107573506-A Polyimide precursor, polyimides, polyimide film, varnish and substrate 宇部兴产株式会社 2018-01-12 CN disclosed
US-5491201-A HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed
US-5338828-A Mesogenic cyclic imino ether-containing compositions and polymerization products thereof THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed
US-5281675-A Liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1994-01-25 US disclosed