SCHEMBL900378

SCHEMBL900378

C/C(=C\c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.65
ESR2 Q92731 2/20 0.65
PTGS1 P23219 9/20 0.50
PTGS2 P35354 7/20 0.50
NQO2 P16083 6/20 0.50
CYP19A1 P11511 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
GFER P55789 1/20 0.46
ALOX5 P09917 1/20 0.42
APP P05067 1/20 0.41
TUBB1 Q9H4B7 1/20 0.40
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900379 1.00 ESR1 (0.65) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900960 0.92 ESR1 (0.81) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900999 0.92 ESR1 (0.81) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900961 0.92 ESR1 (0.81) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900998 0.92 ESR1 (0.81) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8939242 0.90 ESR1 (0.53) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900811 0.90 ESR1 (0.53) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL900810 0.90 ESR1 (0.53) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL901042 0.89 ALDH1A1 (0.58) ESR1ESR2NPC1RAB9AALDH1A1
SCHEMBL9255978 0.89 ESR1 (0.53) ESR1ESR2PTGS1PTGS2NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5414125-A Epoxy resin curing agent THE DOW CHEMICAL COMPANY (US) 1995-05-09 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-20250340753-A1 THIN CORROSION PROTECTIVE COATINGS INCORPORATING POLYAMIDOAMINE POLYMERS HENKEL AG & CO KGAA (DE) 2025-11-06 US disclosed
US-12365812-B2 Thin corrosion protective coatings incorporating polyamidoamine polymers HENKEL AG & CO. KGAA (DE) 2025-07-22 US disclosed
WO-2025038342-A1 DUAL CURE EPOXY COATINGS AND METHODS OF MAKING THE SAME SWIMC LLC (US) 2025-02-20 WO disclosed
US-20240199911-A1 HYBRID DUAL CURE COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-06-20 US disclosed
EP-4314115-A1 HYBRID DUAL CURE COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-02-07 EP disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
WO-2023150473-A1 POLYCARBONATE-BASED POLYURETHANE TOPCOATS PRC-DESOTO INTERNATIONAL, INC. (US) 2023-08-10 WO disclosed
US-20210388231-A1 THIN CORROSION PROTECTIVE COATINGS INCORPORATING POLYAMIDOAMINE POLYMERS HENKEL AG & CO. KGAA (DE) 2021-12-16 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
US-5206321-A Polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US disclosed
WO-1992018460-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1992-10-29 WO disclosed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed