SCHEMBL900810

SCHEMBL900810

C/C(=C\c1ccccc1)c1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.53
ESR2 Q92731 1/20 0.53
CYP1B1 Q16678 1/20 0.49
CYP19A1 P11511 2/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
GFER P55789 1/20 0.46
NQO2 P16083 5/20 0.44
PTGS1 P23219 5/20 0.44
PTGS2 P35354 4/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
AKR1C3 P42330 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900811 1.00 ESR1 (0.53) ESR1ESR2CYP1B1CYP19A1MAOA
SCHEMBL8939242 0.92 ESR1 (0.53) ESR1ESR2CYP1B1CYP19A1MAOA
SCHEMBL900379 0.90 ESR1 (0.65) ESR1ESR2CYP19A1NPC1RAB9A
SCHEMBL900378 0.90 ESR1 (0.65) ESR1ESR2CYP19A1NPC1RAB9A
SCHEMBL7803180 0.89 ESR1 (0.64) ESR1ESR2NPC1RAB9ANQO2
SCHEMBL726321 0.85 ESR1 (0.58) ESR1ESR2NQO2PTGS1PTGS2
SCHEMBL1225178 0.85 ESR1 (0.58) ESR1ESR2NQO2PTGS1PTGS2
SCHEMBL726320 0.85 ESR1 (0.58) ESR1ESR2NQO2PTGS1PTGS2
SCHEMBL901043 0.83 ALDH1A1 (0.58) ESR1ESR2NPC1RAB9AALDH1A1
SCHEMBL900988 0.83 ALDH1A1 (0.58) ESR1ESR2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
US-20190211202-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-11 US disclosed
EP-3500627-A1 ADDUCTS AND USES THEREOF Huntsman Advanced Materials Americas LLC (US) 2019-06-26 EP disclosed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
WO-2018035397-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2018-02-22 WO disclosed
EP-2621992-B1 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF BLUE CUBE IP LLC (US) 2017-07-26 EP disclosed
US-5248758-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5206321-A Polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
US-5077380-A Mesogenic cyanate functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-12-31 US disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed