Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004116 | 0.88 | TRPA1 (0.56) | TRPA1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL9004135 | 0.86 | TRPA1 (0.70) | TRPA1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL1499452 | 0.83 | TRPA1 (1.00) | TRPA1MAPTMEN1KMT2AMAOB | |
| SCHEMBL1499454 | 0.83 | TRPA1 (1.00) | TRPA1MAPTMEN1KMT2AMAOB | |
| SCHEMBL4452015 | 0.83 | TRPA1 (1.00) | TRPA1MAPTMEN1KMT2AMAOB | |
| SCHEMBL9004187 | 0.83 | TRPA1 (0.71) | TRPA1CYP1A2MAPTMAOBSMN1; SMN2 | |
| SCHEMBL9004146 | 0.83 | TRPA1 (0.50) | TRPA1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL9004042 | 0.79 | TRPA1 (0.47) | TRPA1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL9004122 | 0.75 | HTR2A (0.45) | TRPA1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL9004121 | 0.75 | HTR2A (0.45) | TRPA1CYP1A2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| CN-1100716-A | Basic ethers and process for the preparation thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-29 | — | — | CN | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |