Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004115 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BTRPA1UTS2R | |
| SCHEMBL9004122 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BTRPA1UTS2R | |
| SCHEMBL9004100 | 0.90 | HTR2A (0.46) | HTR2AHTR2CHTR2BTRPA1UTS2R | |
| SCHEMBL9004149 | 0.89 | KCNH2 (0.43) | HTR2AHTR2CHTR2BTRPA1MAPT | |
| SCHEMBL9412227 | 0.89 | KCNH2 (0.43) | HTR2AHTR2CHTR2BTRPA1MAPT | |
| SCHEMBL9412273 | 0.87 | HTR2A (0.43) | HTR2AHTR2CHTR2BUTS2RMAPT | |
| SCHEMBL9004144 | 0.80 | UTS2R (0.39) | HTR2AHTR2CHTR2BUTS2RMAPT | |
| SCHEMBL9004126 | 0.80 | BCHE (0.49) | HTR2AHTR2CHTR2BTRPA1ACHE | |
| SCHEMBL9004142 | 0.79 | KCNH2 (0.42) | HTR2AHTR2CHTR2BTRPA1MAPT | |
| SCHEMBL9004096 | 0.78 | ACHE (0.38) | UTS2RMAPTACHENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |