Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004259 | 1.00 | HDAC3 (0.57) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL31123118 | 0.83 | KDM1A (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL29795163 | 0.83 | KDM1A (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL343282 | 0.83 | KDM1A (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL19297268 | 0.81 | ALDH1A1 (0.62) | LMNAMAPTALDH1A1MAPK1ALDH2 | |
| SCHEMBL18076888 | 0.81 | KDM1A (0.62) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5726715 | 0.81 | KDM1A (0.62) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| Potassium SCHEMBL30611014 | 0.81 | KDM1A (0.62) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL14288794 | 0.78 | MAOA (0.64) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL15805952 | 0.78 | PIM1 (0.58) | HDAC3TUBB4ATUBBTUBA3CHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571806-A | Dibenz[b,f][1,4]oxazepin(and thiazepin)-11(10H)-ones and-thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0419861-B1 | Use of dibenz[b,f][1,4]oxazepin (and thiazepin)-11(10H)-ones and -thiones in the preparation of a pharmaceutical composition for the prevention or treatment of aids | BOEHRINGER INGELHEIM PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0419861-A2 | Use of dibenz[b,f][1,4]oxazepin (and thiazepin)-11(10H)-ones and -thiones in the preparation of a pharmaceutical composition for the prevention or treatment of aids | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-04-03 | — | — | EP | disclosed |