Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907472 | 0.79 | APP (0.59) | APPCA12CA1CA9HTT | |
| SCHEMBL13733324 | 0.77 | APP (0.58) | APPL3MBTL1MAPTSNCAMEN1 | |
| SCHEMBL13020459 | 0.76 | APP (0.45) | APPCA12CA1CA9HTT | |
| SCHEMBL5144699 | 0.73 | APP (0.44) | APPL3MBTL1MAPTSNCAMEN1 | |
| SCHEMBL5258061 | 0.73 | HCRTR2 (0.45) | KMT2AALDH1A1BCHEACHE | |
| SCHEMBL15326042 | 0.71 | BCHE (0.38) | CA12CA1CA9ALDH1A1BCHE | |
| SCHEMBL5142551 | 0.70 | MEN1 (0.41) | APPCA12CA1CA9L3MBTL1 | |
| SCHEMBL13294955 | 0.70 | APP (0.35) | APPL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1852056 | 0.69 | CYP2A6 (0.42) | APPCA12CA1CA9MAPT | |
| SCHEMBL5259457 | 0.69 | CNR2 (0.45) | MAPTALDH1A1HPGDBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008522795-A | — | — | 2008-07-03 | — | — | JP | claimed |
| EP-1838431-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | California Institute of Technology (US) | 2007-10-03 | — | — | EP | claimed |
| WO-2006071470-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-07-06 | — | — | WO | claimed |
| EP-2585211-A2 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | ABX Advanced Biochemical Compounds GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012041305-A2 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |
| EP-1838431-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | California Institute of Technology (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006071470-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-07-06 | — | — | WO | disclosed |
| EP-1667794-A2 | SYSTEM AND METHOD FOR SYNTHESIS OF MOLECULAR IMAGING PROBES INCLUDING FDG | Molecular Technologies Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2004093652-A2 | SYSTEM AND METHOD FOR SYNTHESIS OF MOLECULAR IMAGING PROBES INCLUDING FDG | MOLECULAR TECHNOLOGIES, INC. (US) | 2004-11-04 | — | — | WO | disclosed |