SCHEMBL2756476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL225916	0.92	MAPT (0.59)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL29640485	0.92	MAPT (0.59)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL225814	0.92	NOX1 (0.47)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL239549	0.86	NOX1 (0.65)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL225829	0.86	NOX1 (0.65)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL2756739	0.85	NOX1 (0.50)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL9980103	0.85	NOX1 (0.54)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL10890272	0.81	NOX1 (0.61)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL24255127	0.81	MAPT (0.50)	NOX1MAPTGAAMEN1KMT2A
	SCHEMBL9391898	0.81	SNCA (0.55)	NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.