Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004632 | 0.87 | SENP6 (0.55) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL9004630 | 0.87 | SENP6 (0.55) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL9004676 | 0.83 | ALDH1A1 (0.55) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL9004623 | 0.83 | KMT2A (0.47) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL9004603 | 0.80 | SENP6 (0.51) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL8856659 | 0.79 | SENP6 (0.76) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL8856663 | 0.79 | SENP6 (0.76) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL8856707 | 0.77 | SENP6 (0.57) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL8856704 | 0.77 | SENP6 (0.57) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A | |
| SCHEMBL9004649 | 0.76 | SENP6 (0.56) | CYP1A2CYP2C19SENP6SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571843-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1996-11-05 | — | — | US | disclosed |
| EP-0566445-B1 | Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA LAB SA (FR) | 1996-02-07 | — | — | EP | disclosed |
| EP-0566445-A1 | Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA (FR) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993020045-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR THE PREPARATION OF SAME AND THEIR APPLICATION AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |