Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9038240 | 0.99 | KMT2A (0.49) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9004632 | 0.86 | SENP6 (0.55) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL9004630 | 0.86 | SENP6 (0.55) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL9004785 | 0.85 | KMT2A (0.52) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL8667830 | 0.83 | SENP6 (0.61) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9004613 | 0.80 | SENP6 (0.67) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9004617 | 0.80 | TRPV1 (0.48) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9004669 | 0.80 | TRPV1 (0.48) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9004721 | 0.80 | SENP6 (0.60) | KMT2AALDH1A1MEN1MAPTHSD17B10 | |
| SCHEMBL9004684 | 0.79 | SENP6 (0.62) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571843-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1996-11-05 | — | — | US | disclosed |
| WO-1993020045-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR THE PREPARATION OF SAME AND THEIR APPLICATION AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |