Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004754 | 0.85 | STING1 (0.50) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL9004715 | 0.85 | MAPT (0.53) | KMT2AALDH1A1MEN1IDO1LMNA | |
| SCHEMBL9004676 | 0.84 | ALDH1A1 (0.55) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL9004665 | 0.77 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1IDO1LMNA | |
| SCHEMBL9004623 | 0.76 | KMT2A (0.47) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL8856667 | 0.76 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL5442089 | 0.74 | KMT2A (0.89) | KMT2AALDH1A1MEN1KDM4EIDO1 | |
| SCHEMBL31388373 | 0.74 | KMT2A (0.89) | KMT2AALDH1A1MEN1KDM4EIDO1 | |
| SCHEMBL16566477 | 0.73 | KMT2A (1.00) | KMT2AALDH1A1MEN1KDM4EIDO1 | |
| SCHEMBL9004636 | 0.73 | CYP1A2 (0.51) | KMT2AALDH1A1MEN1IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571843-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1996-11-05 | — | — | US | disclosed |