Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9036285 | 0.98 | SENP6 (0.43) | SENP6NPSR1KDM4EGAAALDH1A1 | |
| SCHEMBL9004649 | 0.82 | SENP6 (0.56) | SENP6NPSR1KDM4EGAAALDH1A1 | |
| SCHEMBL9004643 | 0.82 | SENP6 (0.56) | SENP6NPSR1KDM4EGAAALDH1A1 | |
| SCHEMBL9004644 | 0.76 | KMT2A (0.50) | SENP6NPSR1KDM4EALDH1A1KMT2A | |
| Water SCHEMBL9038240 | 0.75 | KMT2A (0.49) | SENP6NPSR1KDM4EALDH1A1KMT2A | |
| SCHEMBL9004602 | 0.74 | MAPT (0.45) | SENP6KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL9004600 | 0.74 | MAPT (0.45) | SENP6KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL9004597 | 0.74 | MAPT (0.64) | SENP6KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL8856720 | 0.73 | SENP6 (0.70) | SENP6KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL9004785 | 0.71 | KMT2A (0.52) | SENP6KDM4EGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571843-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1996-11-05 | — | — | US | disclosed |
| WO-1993020045-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR THE PREPARATION OF SAME AND THEIR APPLICATION AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |