SCHEMBL900505

SCHEMBL900505

CC(C)(c1cc(Br)c(N)c(Br)c1)c1cc(Br)c(C(=O)O)c(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.47
ALOX12 P18054 2/20 0.47
TSHR P16473 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
CASP1 P29466 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CHEK1 O14757 1/20 0.41
DAPK3 O43293 1/20 0.41
RET P07949 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41
PDGFRA P16234 1/20 0.41
KDR P35968 1/20 0.41
MAPK8 P45983 1/20 0.41
RPS6KA3 P51812 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11555612 0.91 HSD17B10 (0.56) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL901084 0.84 ALOX15 (0.70) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL6906660 0.82 ALOX15 (0.58) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL901081 0.77 TSHR (0.79) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL20490678 0.72 GSK3B (0.40) TSHRHIF1AHSD17B10GSK3BCYP2C9
SCHEMBL900864 0.72 MAPT (0.48) ALOX15TSHRHIF1AHSD17B10ALDH1A1
SCHEMBL10447605 0.72 ESR1 (0.47) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL7821421 0.71 GSK3B (0.39) ALOX15ALOX12TSHRHIF1AHSD17B10
Bicarbonate SCHEMBL11306999 0.71 ALOX15 (0.83) ALOX15ALOX12TSHRHIF1AHSD17B10
SCHEMBL5581647 0.70 CYP3A4 (0.48) ALOX15ALOX12TSHRHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
CN-111801388-A High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2020-10-20 CN disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
EP-2621992-B1 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF BLUE CUBE IP LLC (US) 2017-07-26 EP disclosed
US-9340702-B2 Coating compositions BLUE CUBE IP LLC (US) 2016-05-17 US disclosed
US-9284434-B2 Epoxy resin compositions BLUE CUBE IP LLC (US) 2016-03-15 US disclosed
EP-2621990-B1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM BLUE CUBE IP LLC (US) 2016-02-24 EP disclosed
US-9255177-B2 Hybrid epoxy resin adducts BLUE CUBE IP LLC (US) 2016-02-09 US disclosed
WO-2009143038-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-26 WO disclosed
WO-2009142898-A1 ADDUCTS OF EPOXY RESINS AND PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-26 WO disclosed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US disclosed
US-5414121-A Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US disclosed
US-5276184-A Curing agents for epoxy resins for thermosetting resins THE DOW CHEMICAL COMPANY (US) 1994-01-04 US disclosed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed