Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306804 | 0.80 | IMPDH2 (0.48) | MAOAMAOBIMPDH2IMPDH1DYRK1A | |
| SCHEMBL17297038 | 0.80 | IMPDH2 (0.48) | MAOAMAOBIMPDH2IMPDH1DYRK1A | |
| SCHEMBL11640804 | 0.77 | TSHR (0.48) | MAOAMAOBIMPDH2IMPDH1DYRK1A | |
| SCHEMBL28230714 | 0.76 | ALDH1A1 (0.52) | IMPDH2IMPDH1DYRK1ACA1CA2 | |
| SCHEMBL21808809 | 0.75 | ESR2 (0.43) | MAOAMAOBIMPDH2IMPDH1DYRK1A | |
| SCHEMBL28511 | 0.74 | ALDH1A1 (0.44) | CA1CA2KDM4EALDH1A1TSHR | |
| SCHEMBL18889038 | 0.74 | AR (0.45) | IMPDH2IMPDH1DYRK1AKDM4EALDH1A1 | |
| SCHEMBL29352635 | 0.74 | ALDH1A1 (0.44) | CA1CA2KDM4EALDH1A1TSHR | |
| SCHEMBL21297906 | 0.73 | IMPDH2 (0.42) | MAOAMAOBIMPDH2IMPDH1DYRK1A | |
| SCHEMBL21298498 | 0.73 | IMPDH2 (0.42) | MAOAMAOBIMPDH2IMPDH1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502723-B1 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5438135-A | Fluorescence analysis | HITACHI CHEMICAL COMPANY (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0502723-A2 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |