Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375825 | 0.87 | TSHR (0.50) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL578310 | 0.84 | CYP2A6 (0.50) | TSHRNPY5RCCNT1CDK9 | |
| SCHEMBL16062693 | 0.81 | POLB (0.46) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL2493713 | 0.81 | TSHR (0.44) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL10866160 | 0.80 | NQO1 (0.52) | TSHRNPY5RCCNT1CDK9POLB | |
| SCHEMBL23822678 | 0.79 | TSHR (0.43) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL25923558 | 0.79 | TSHR (0.43) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL915242 | 0.79 | TSHR (0.43) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL13059994 | 0.78 | NPY5R (0.42) | TSHRNPY5RCCNT1CDK9TLR8 | |
| SCHEMBL13981237 | 0.78 | ENPP2 (0.51) | TSHRNPY5RCCNT1CDK9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496834-A | PEPTIDE DERIVATIVES AS CATHEPSIN L INHIBITORS AND INHIBITORS OF BONE RESORPTION OR TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-05 | — | — | US | disclosed |