Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 10/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391628 | 0.90 | PRKCQ (0.64) | PRKCQTTRPIM1PIM3PIM2 | |
| SCHEMBL20031456 | 0.78 | KDM4E (0.47) | PRKCQTTRKDM4EALOX15TSHR | |
| SCHEMBL8965879 | 0.78 | PRKCQ (1.00) | PRKCQ | |
| Oxalic Acid SCHEMBL9005357 | 0.77 | PRKCQ (0.48) | PRKCQPIM1PIM3PIM2 | |
| SCHEMBL16834258 | 0.77 | ALDH1A1 (0.47) | TTRKDM4EALOX15TSHRACMSD | |
| SCHEMBL20055871 | 0.77 | ALDH1A1 (0.47) | TTRKDM4EALOX15TSHRACMSD | |
| SCHEMBL3469975 | 0.77 | KDM4E (0.46) | PRKCQTTRKDM4EALOX15TSHR | |
| SCHEMBL31480075 | 0.77 | TTR (0.47) | PRKCQTTRKDM4EALOX15TSHR | |
| SCHEMBL7393229 | 0.76 | PRKCQ (0.52) | PRKCQALOX15TSHRPIM1PIM3 | |
| SCHEMBL9005452 | 0.75 | PRKCQ (0.63) | PRKCQTTRKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576320-A | 1-heteruarylazetidines and -pyrrolidines, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-11-19 | — | — | US | disclosed |
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5410057-A | 1-heteroarylazetidines and -pyrrolidines | SANOFI (FR) | 1995-04-25 | — | — | US | disclosed |