Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836939 | 0.79 | GNE (0.60) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL14879835 | 0.79 | GNE (0.56) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL20031106 | 0.79 | RBP4 (0.54) | SMPD3RBP4HCRTR1HCRTR2 | |
| SCHEMBL31480075 | 0.78 | TTR (0.47) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL9005458 | 0.78 | PRKCQ (0.62) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL2638003 | 0.78 | TTR (0.53) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL16834258 | 0.78 | ALDH1A1 (0.47) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL17373798 | 0.78 | TTR (0.53) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL20055871 | 0.78 | ALDH1A1 (0.47) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL3469975 | 0.78 | KDM4E (0.46) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |