Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005492 | 1.00 | HDAC1 (0.50) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL5219915 | 0.83 | HDAC1 (0.53) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL5219928 | 0.83 | HDAC1 (0.53) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL6821848 | 0.83 | KDR (0.53) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL6821842 | 0.83 | KDR (0.53) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| Hydrochloric Acid SCHEMBL6821851 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL6821096 | 0.78 | APP (0.54) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL6821093 | 0.78 | APP (0.54) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL9005504 | 0.78 | KDR (0.49) | HDAC1HDAC6HDAC8KDRNPFFR1 | |
| SCHEMBL8997537 | 0.77 | APP (0.59) | HDAC1HDAC6HDAC8KDRNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585493-A | PARASITICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5371231-A | Endoparasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |