Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219928 | 0.82 | HDAC1 (0.53) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL6821842 | 0.82 | KDR (0.53) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL6821848 | 0.82 | KDR (0.53) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL5219915 | 0.82 | HDAC1 (0.53) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| Hydrochloric Acid SCHEMBL6821851 | 0.81 | HDAC1 (0.52) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL9005500 | 0.78 | HDAC1 (0.50) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL9005492 | 0.78 | HDAC1 (0.50) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL6821093 | 0.77 | APP (0.54) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL6821096 | 0.77 | APP (0.54) | KDRHDAC1HDAC8HDAC6NPFFR1 | |
| SCHEMBL8997537 | 0.76 | APP (0.59) | KDRHDAC1HDAC8HDAC6NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585493-A | PARASITICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5371231-A | Endoparasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |