Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005515 | 1.00 | HDAC1 (0.41) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL9005516 | 0.83 | PTGS2 (0.51) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL9005523 | 0.83 | PTGS2 (0.51) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL6822172 | 0.81 | CA1 (0.50) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL6822168 | 0.81 | CA1 (0.50) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL6821923 | 0.81 | HDAC1 (0.45) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL6821922 | 0.81 | HDAC1 (0.45) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL30560915 | 0.80 | HDAC1 (0.44) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL933658 | 0.76 | MAOB (0.51) | HDAC1HDAC6HDAC8GSRMAPT | |
| SCHEMBL9005522 | 0.76 | HDAC1 (0.41) | HDAC1HDAC6HDAC8GSRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585493-A | PARASITICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5371231-A | Endoparasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |