Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005523 | 1.00 | PTGS2 (0.51) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL9005509 | 0.83 | HDAC1 (0.41) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL9005515 | 0.83 | HDAC1 (0.41) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL15958497 | 0.81 | PTGS2 (0.47) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL1124437 | 0.80 | PTGS2 (0.55) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL7004850 | 0.80 | PTGS2 (0.55) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL1124438 | 0.80 | PTGS2 (0.55) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL7004841 | 0.80 | PTGS2 (0.55) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL9652685 | 0.79 | PTGS2 (0.54) | PTGS2HDAC1HDAC6HDAC8GSR | |
| SCHEMBL9779303 | 0.75 | PTGS2 (0.69) | PTGS2MAPTLMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585493-A | PARASITICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5371231-A | Endoparasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |