Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005571 | 1.00 | NPFFR2 (0.47) | NPFFR2NPFFR1NOTUMKDRHDAC1 | |
| SCHEMBL9106606 | 0.84 | AR (0.50) | NPFFR2NPFFR1NOTUMKDRHDAC1 | |
| SCHEMBL9106595 | 0.84 | AR (0.50) | NPFFR2NPFFR1NOTUMKDRHDAC1 | |
| SCHEMBL2325460 | 0.83 | NPFFR2 (0.50) | NPFFR2NPFFR1NOTUMKDRHDAC1 | |
| SCHEMBL2325457 | 0.83 | NPFFR2 (0.50) | NPFFR2NPFFR1NOTUMKDRHDAC1 | |
| SCHEMBL4716231 | 0.81 | KDM4E (0.40) | KDM4EAPPENPP2FDPSCTSS | |
| SCHEMBL4716235 | 0.81 | KDM4E (0.40) | KDM4EAPPENPP2FDPSCTSS | |
| SCHEMBL4716233 | 0.81 | KDM4E (0.40) | KDM4EAPPENPP2FDPSCTSS | |
| SCHEMBL10734385 | 0.78 | ALDH1A1 (0.48) | NPFFR2KDM4EENPP2FDPS | |
| SCHEMBL2779298 | 0.78 | ALDH1A1 (0.48) | NPFFR2KDM4EENPP2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585493-A | PARASITICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5428049-A | Parasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| US-5371231-A | Endoparasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| US-4785007-A | ANTIDEPRESSANTS, P | LABORATOIRES HOECHST S.A. (FR) | 1988-11-15 | — | — | US | disclosed |