SCHEMBL9005645

SCHEMBL9005645

O=C(O)COc1cccc2c1CCC2C/C=N\OC(c1ccccc1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 18/20 0.74
TBXAS1 P24557 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9005755 1.00 PTGIR (0.74) PTGIRTBXAS1
SCHEMBL9005777 0.94 PTGIR (0.84) PTGIRTBXAS1
SCHEMBL9005686 0.94 PTGIR (0.84) PTGIRTBXAS1
SCHEMBL9005672 0.83 PTGIR (1.00) PTGIRTBXAS1
SCHEMBL9005666 0.83 PTGIR (1.00) PTGIRTBXAS1
SCHEMBL9005721 0.81 PTGIR (0.57) PTGIR
SCHEMBL9005660 0.81 PTGIR (0.57) PTGIR
SCHEMBL9048983 0.78 PTGIR (0.57) PTGIRTBXAS1
SCHEMBL9005740 0.78 PTGIR (0.77) PTGIRTBXAS1
SCHEMBL9005753 0.78 PTGIR (0.77) PTGIRTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578847-B1 Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists ONO PHARMACEUTICAL CO (JP) 1996-10-09 EP claimed
EP-0578847-A1 Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 1994-01-19 EP claimed