Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.57 |
| ▸ | PPARD | Q03181 | 13/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005721 | 1.00 | PTGIR (0.57) | PTGIRPPARDADRB1ADRB3PPARA | |
| SCHEMBL9005770 | 0.83 | PTGIR (0.68) | PTGIRADRB1ADRB3 | |
| SCHEMBL9005700 | 0.83 | PTGIR (0.68) | PTGIRADRB1ADRB3 | |
| SCHEMBL9005739 | 0.83 | PTGIR (0.68) | PTGIRADRB1ADRB3 | |
| SCHEMBL9005645 | 0.81 | PTGIR (0.74) | PTGIR | |
| SCHEMBL9005755 | 0.81 | PTGIR (0.74) | PTGIR | |
| SCHEMBL9005686 | 0.77 | PTGIR (0.84) | PTGIR | |
| SCHEMBL9005777 | 0.77 | PTGIR (0.84) | PTGIR | |
| SCHEMBL8354931 | 0.75 | PTGIR (0.88) | PTGIRPPARA | |
| SCHEMBL8354932 | 0.75 | PTGIR (0.88) | PTGIRPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | claimed |