Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005957 | 0.84 | PPARA (0.54) | PPARAPPARGNPC1RAB9AMAPT | |
| SCHEMBL7609215 | 0.79 | PPARA (0.45) | PPARAPPARGPPARDAOC3 | |
| SCHEMBL9005912 | 0.78 | PPARG (0.60) | PPARAPPARGNPC1RAB9AMAPT | |
| SCHEMBL4747685 | 0.78 | FFAR1 (0.52) | PPARAPPARGRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4746469 | 0.76 | PPARG (0.73) | PPARAPPARGPPARD | |
| SCHEMBL4744152 | 0.75 | PPARG (0.55) | PPARAPPARGPPARD | |
| SCHEMBL9005959 | 0.75 | PPARA (0.60) | PPARAPPARGFFAR1PPARDNOTUM | |
| SCHEMBL6970285 | 0.72 | PPARG (0.65) | PPARAPPARGPPARD | |
| SCHEMBL10115511 | 0.72 | NPC1 (0.93) | PPARAPPARGNPC1RAB9AMAPT | |
| SCHEMBL1299974 | 0.72 | RAB9A (0.61) | PPARAPPARGNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |