Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.64 |
| ▸ | PPARA | Q07869 | 16/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156966 | 0.93 | PPARA (0.61) | PPARGPPARA | |
| SCHEMBL9005900 | 0.92 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL8859196 | 0.91 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL9005899 | 0.89 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL9005933 | 0.86 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL9005908 | 0.83 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL6604087 | 0.82 | PPARG (0.66) | PPARGPPARA | |
| SCHEMBL9258855 | 0.82 | FFAR1 (0.67) | PPARGPPARA | |
| SCHEMBL9005928 | 0.82 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL13718146 | 0.81 | PPARA (0.93) | PPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |