Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 5/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025046 | 1.00 | TBXA2R (0.43) | TBXA2RPTGDRTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9006194 | 0.93 | TBXAS1 (0.48) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9024135 | 0.93 | TBXAS1 (0.48) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9006241 | 0.92 | TBXAS1 (0.48) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9024494 | 0.92 | TBXAS1 (0.48) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9025186 | 0.91 | TBXAS1 (0.40) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9006141 | 0.91 | TBXAS1 (0.40) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9024389 | 0.91 | TBXAS1 (0.46) | TBXA2RTBXAS1 | |
| SCHEMBL9006132 | 0.91 | TBXAS1 (0.46) | TBXA2RTBXAS1 | |
| SCHEMBL9006313 | 0.88 | TBXAS1 (0.47) | TBXA2RTBXAS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5514701-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |