Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006241 | 1.00 | TBXAS1 (0.48) | TBXAS1TBXA2RPTGDR | |
| SCHEMBL9024043 | 0.94 | TBXAS1 (0.56) | TBXAS1TBXA2R | |
| SCHEMBL9006081 | 0.94 | TBXAS1 (0.56) | TBXAS1TBXA2R | |
| Water SCHEMBL2925887 | 0.93 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL8657761 | 0.93 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL8657765 | 0.93 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| SCHEMBL9025046 | 0.92 | TBXA2R (0.43) | TBXAS1TBXA2RPTGDR | |
| SCHEMBL9006185 | 0.92 | TBXA2R (0.43) | TBXAS1TBXA2RPTGDR | |
| SCHEMBL9006204 | 0.91 | TBXAS1 (0.48) | TBXAS1TBXA2RPTGDR | |
| SCHEMBL9006208 | 0.91 | TBXAS1 (0.48) | TBXAS1TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |