Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023789 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL10447702 | 0.84 | ALDH1A1 (0.40) | ALDH1A1GAACTSLCTSBCTSK | |
| Bromide SCHEMBL9006253 | 0.81 | PTGER4 (0.40) | ALDH1A1KDM4EMEN1USP2MAPT | |
| Bromide SCHEMBL9024989 | 0.81 | PTGER4 (0.40) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL9006096 | 0.79 | PTGDR (0.47) | ALDH1A1MEN1USP2KMT2A | |
| SCHEMBL9024719 | 0.79 | TBXA2R (0.47) | ALDH1A1TSHRCA1CA2MEN1 | |
| SCHEMBL9006133 | 0.79 | TBXA2R (0.47) | ALDH1A1TSHRCA1CA2MEN1 | |
| SCHEMBL9006089 | 0.79 | PTGDR (0.47) | ALDH1A1MEN1USP2KMT2A | |
| SCHEMBL9006075 | 0.78 | PTGDR (0.46) | ALDH1A1GAACA1CA2PKM | |
| SCHEMBL9024635 | 0.78 | PTGDR (0.46) | ALDH1A1GAACA1CA2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5514701-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |