2-Chlorophenol

2-Chlorophenol

SCHEMBL9006411

CCCc1cccc(O)c1Cl.Oc1ccccc1Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.48
TAAR1 Q96RJ0 3/20 0.42
HTR1A P08908 1/20 0.41
IAPP P10997 1/20 0.38
CFTR P13569 2/20 0.38
AR P10275 1/20 0.37
PNMT P11086 1/20 0.37
ELANE P08246 1/20 0.37
CTSG P08311 1/20 0.37
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
HSPA5 P11021 1/20 0.36
KAT8 Q9H7Z6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631373 0.91 TSHR (0.46) TSHRTAAR1HTR1AIAPPELANE
2-Chlorophenol SCHEMBL27518189 0.89 BID (0.50) ALDH1A1TSHRBIDMCL1BCL2L1
2-Chlorophenol SCHEMBL15717544 0.86 ALDH1A1 (0.52) ALDH1A1TSHRHTR1AIAPPCFTR
SCHEMBL6912401 0.86 GABRA1 (0.47) TSHRHTR1AIAPPELANECTSG
Parachlorophenol SCHEMBL15717394 0.80 BID (0.46) ALDH1A1TSHRBIDMCL1BCL2L1
SCHEMBL574234 0.80 BID (0.50) TSHRIAPPELANECTSGBID
SCHEMBL8082929 0.79 TAAR1 (0.63) ALDH1A1TSHRTAAR1PNMT
SCHEMBL7605260 0.79 GABRA1 (0.40) TSHRHTR1AIAPPELANECTSG
SCHEMBL573936 0.79 BID (0.57) TSHRELANECTSGBIDMCL1
Ammonia Solution, Strong SCHEMBL14718471 0.77 TAAR1 (0.61) ALDH1A1TSHRTAAR1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2919749-A1 ORAL CARE COMPOSITIONS McNeil-PPC, Inc. (US) 2015-09-23 EP disclosed
WO-2014078198-A1 ORAL CARE COMPOSITIONS MCNEIL-PPC, INC. (US) 2014-05-22 WO disclosed
EP-0735856-A1 CONCENTRATED MOUTHRINSE FOR EFFICIENT DELIVERY OF ANTIMICROBIALS THE PROCTER & GAMBLE COMPANY (US) 1996-10-09 EP disclosed
WO-1995017159-A1 CONCENTRATED MOUTHRINSE FOR EFFICIENT DELIVERY OF ANTIMICROBIALS THE PROCTER & GAMBLE COMPANY (US) 1995-06-29 WO disclosed