SCHEMBL9006609

SCHEMBL9006609

O=C(/C=C/c1ccc(OC(F)=C(F)F)cc1)/C=C/c1cccc(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.54
CYP1A2 P05177 1/20 0.51
P4HB P07237 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
HSP90AA1 P07900 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NFE2L2 Q16236 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
HTT P42858 1/20 0.46
THRB P10828 1/20 0.46
MAOA P21397 1/20 0.46
KDM4E B2RXH2 1/20 0.45
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006617 1.00 MAOB (0.54) MAOBCYP1A2P4HBMEN1LMNA
SCHEMBL9006545 0.87 CYP1A2 (0.69) MAOBCYP1A2P4HB
SCHEMBL9006549 0.87 CYP1A2 (0.69) MAOBCYP1A2P4HB
SCHEMBL9006616 0.83 F3 (0.59) MAOBCYP1A2MEN1LMNAMAPT
SCHEMBL9006612 0.83 F3 (0.59) MAOBCYP1A2MEN1LMNAMAPT
SCHEMBL9006591 0.83 F3 (0.58) CYP1A2LMNAMAPTKMT2ATHRB
SCHEMBL9006668 0.83 F3 (0.58) CYP1A2LMNAMAPTKMT2ATHRB
SCHEMBL12002074 0.83 P4HB (0.66) MAOBCYP1A2P4HBMEN1LMNA
SCHEMBL17061419 0.83 P4HB (0.66) MAOBCYP1A2P4HBMEN1LMNA
SCHEMBL9006726 0.81 CYP1A2 (0.60) MAOBCYP1A2P4HBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed